CHIRALITY 2025 Neel Moudgal (University of Michigan) Jessica Ma (University of Michigan) Hongjin Du (Cornell University) Pepijn Rang (AMOLF) CD 2025 Inkarat Atirojwanich (University of Rennes) Marco Bertuolo (University of Bordeaux) Aleksandra Kołodziejczyk (Jagiellonian University) Krisztián Cserepes (University of Debrecen) At this conference, Rina implemented a new Award that exemplifies Larry’s character – thrust for knowledge, […]

Kick off the fall by getting into the latest publications featuring our signature technologies: VCD & ROA! (If we missed your paper, we’d love to include it on our next list – please send us the DOI!)

We are pleased to share a newly released Special Issue dedicated to celebrating the career and contributions of Professor Laurence A. Nafie. This collection presents Professor Nafie’s contributions to the field.

MEASURING ALL 4 FORMS OF ROA – ICP, SCP, DCP1 & DCP2 Includes a specialized version of ProtaCal software for 4-form spectral visualization and processing

BioTools Inc. is pleased to spotlight a newly published peer-reviewed study titled “Biginelli dihydropyrimidines and their acetylated derivatives as L-/T-type calcium channel blockers: Synthesis, enantioseparation, and molecular modeling studies” by M. G. Gündüz & C. Dengiz, et al., appearing in Archiv der Pharmazie. https://onlinelibrary.wiley.com/doi/full/10.1002/ardp.202400584 This research explores a class of Biginelli-derived dihydropyrimidines (DHPMs), structurally related to 1,4-dihydropyridines […]

We’re excited to kick off our 25th Anniversary with some big news—we’ve moved to a brand-new location at 5730 Corporate Way, Ste. 220, West Palm Beach, FL 33407 Our new space allows us to serve you even better, and we can’t wait to welcome you. In addition to our extensive expertise in structure elucidation of […]

NEW CD MODULE! We’re thrilled to announce the launch of our New CD Module! ProtaCAL sets the standard for structure determination with multiple spectroscopic techniques. Biopharma’s #1 choice for Structure (HOS) from Spectroscopy. This CD module is different from all other CD algorithms as it does NOT require knowledge of exact concentration and number of […]

Step into the new year by downloading the newest papers that includes our signature technology of VCD. We truly love all the publications featuring VCD! (and we apologize if we missed your paper – please email us the DOI). Among all these exciting papers, we would like to feature one specifically – a paper by […]

Step into the new year by downloading the newest papers that includes our VCD and ROA technologies Conformational distributions of tetrahydro-2-turoic acid in water at different pH values by theirIR and vibrational circular dichroism spectraYang, Yanqing; Alshalalfeh, Mutasem ; Xu, YunjieSpectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (2024), 307, 123634doi: 10.1016/j.saa.2023.123634 Determining the nanostructure […]

Many small molecule bioactive and marketed drugs are chiral. They are often synthesised from commercially available chiral building blocks. However, chirality is sometimes incorrectly assigned by manufacturers with consequences for the end user ranging from: experimental irreproducibility, wasted time on synthesising the wrong product and reanalysis, to the added cost of purchasing the precursor and resynthesis of the correct stereoisomer.

Many small molecule bioactive and marketed drugs are chiral. They are often synthesised from commercially available chiral building blocks. However, chirality is sometimes incorrectly assigned by manufacturers with consequences for the end user ranging from: experimental irreproducibility, wasted time on synthesising the wrong product and reanalysis, to the added cost of purchasing the precursor and resynthesis of the correct stereoisomer.

BioTools Inc. is delighted to highlight a groundbreaking publication, co-authored by our customers at Jagiellonian University and our co-founder, Prof.  Laurence A. Nafie, in Chemical Communications titled “Exceptionally enhanced Raman optical activity (ROA) of amyloid fibrils and their prefibrillar states”(Vol. 59, 2023, 10793-10796, DOI: 10.1039/D3CC03216G). RSC Publishing The study reveals that amyloid fibrils and their prefibrillar states exhibit an exceptionally […]

We are excited to announce that BioTools has joined Rilas Innovation Center / RISE Lab in Woburn, MA! The facility will provide full lab services and will also include a demonstration lab. Starting with our award-winning VCD instrumentation for determination of absolute configuration of chiral molecules, we will soon add our cutting edge tools for […]